研究方向：慢性阻塞性肺疾病，慢性气道炎症与免疫

研究工作：慢阻肺早期干预药物试验，基于多组学的慢阻肺个体化分型和预后研究，气道中性粒细胞炎症与自身免疫研究

代表性科研项目：

(1) 国家自然科学基金委员会, 青年科学基金项目, 82200044, PR3-BAFF介导中性粒细胞与B细胞互作参与COPD发病机制的研究, 2023-01-01 至 2025-12-31, 在研, 主持

(2) 呼吸疾病国家重点实验室, 自主课题, SKLRD-Z-202317, 基于DIA质谱的慢阻肺急性加重风险分层及预测标志物研究, 2023-01-01 至2025-12-31,在研, 主持

(3) 广东省卫健委, 广东省医学科研基金, A2019459, 痰自身抗体谱IgA对慢阻肺急性加重风险的分层及预测价值研究, 2019-07 至 2021-06, 结题, 主持

(4) 国家自然科学基金委员会, 面上项目, 82270044, 基于定量CT参数机器学习的慢阻肺分型与多维度评价研究, 2023-01-01 至 2026-12-31, 在研, 参与

(5) 国家自然科学基金委员会, 面上项目, 31970112, 多组学技术联合解析慢阻肺急性加重气道菌群宿主互作机制, 2020-01-01 至 2023-12-31, 在研, 参与

(6) 科技部, 国家重点研发计划，重大慢性非传染性疾病防控研究重点专项, 2017YFC1310601, 慢性阻塞性肺疾病急性加重预警与预防策略研究, 2017-07 至 2021-06, 结题, 参与

代表性学术论文（参考文献格式）：

[1] Wang, Fengyan#; Liang, Zhenyu#; Yang, Yuqiong; Zhou, Luqian; Guan, Lili; Wu, Weiliang; Jian g, Mei; Shi, Weijuan; Deng, Kuimiao; Chen, Jianhua; Chen, Rongchang ; Reproducibility of fluid-ph ase measurements in PBS-treated sputum supernatant of healthy and stable COPD subjects,  International Journal of Chron ic Obstructive Pulmonary Disease, 2019, 14: 835-852

[2] Liang, Zhenyu#; Wang, Fengyan#; Zhang, Dongying#; Long, Fei#; Yang, Yuqiong; Gu, Weili; Deng, Kuimiao; Xu, Jiaxuan; Jian, Wenhua; Zhou, Luqian; Shi, Weijuan; Zheng, Jinping; Chen, Xin; Chen, Rongchang ; Sputum and serum autoantibody profiles and their clinical correlation patterns in COP D patients with and without eosinophilic airway inflammation, Journal of Thoracic Disease, 2020, 12(6): 3085-3100

[3] Guoyan Tang#; Fengyan Wang#; Zhenyu Liang#; Cuixia Liang#; Jinling Wang; Yuqiong Yang; WanyiTang; Weijuan Shi; Guoqiang Tang; Kai Yang; Zihui Wang; Qiasheng Li; Hualin Li; Jiaxuan Xu; Deyan Chen; Rongchang Chen ; Correlations of Computed Tomography Measurement of Distal Pulmonary Vascul ar Pruning with Airflow Limitation and Emphysema in COPD Patients, International Journal of Chron ic Obstructive Pulmonary Disease, 2022, Volume 17: 2241-2252

[4] Wang, Zhang#; Liu, Haiyue#; Wang, Fengyan#; Yang, Yuqiong#; Wang, Xiaojuan; Chen, Boxuan; Sta mpfli, Martin R.; Zhou, Hongwei; Shu, Wensheng; Brightling, Christopher E.; Liang, Zhenyu; Chen, Rongchang ; A Refined View of Airway Microbiome in Chronic Obstructive Pulmonary Disease at Speci es and Strain-Levels, Frontiers in Microbiology, 2020, 11: 1758

[5] Liang, Zhenyu#; Long, Fei#; Deng, Kuimiao#; Wang, Fengyan#; Xiao, Jing; Yang, Yuqiong; Zhang, Dongying; Gu, Weili; Xu, Jiaxuan; Jian, Wenhua; Shi, Weijuan; Zheng, Jinping; Chen, Xin; Gao, Yan g; Luo, Qun; Stampfli, Martin R.; Peng, Tao; Chen, Rongchang ; Dissociation between airway and sy stemic autoantibody responses in chronic obstructive pulmonary disease, Annals of Translational M edicine, 2020, 8(15): 918

[6] Fengyan Wang, Zhenyu Liang, Yuqiong Yang, Mei Jiang,Weijuan Shi, Yuqi Li, Rongchang Chen*. Sputum IgA Autoantibodies Predict the Chronic Obstructive Pulmonary Disease Exacerbations.ATS 2019 International Conference. Dallas, May 17-22, 2019.

[7] Wang,, Fengyan; Liang, Zhenyu; Zhou, Yumin; et al. Medical quality control interventions for COPD patients in China: a cluster randomized, controlled trial [J]. Eur Res Soci, 2020, 56:2422.

获奖及个人荣誉：广东省医学科技奖二等奖主要完成人之一，广州市高层次人青年后备人才，美国胸科学会国际学员奖学金。